Disclaimer: This article is purely for informational and educational purposes only and is not intended to be medical advice. Always consult with a licensed medical provider before beginning any new treatment or health-related practice.
If I had a quarter for every time someone asked me in the past two years about psychedelics, ketamine, or microdosing - I’d be well on my way to cashing in on that oversized designer handbag I’ve been eyeing (and maybe even the matching shoes!) Especially with the flood of TikToks, Podcasts, Reddit threads, and documentaries painting microdosing as the next mental wellness revolution.
We’re living in an exciting era where people are rethinking their relationship with mental health, and frankly, the traditional path of antidepressants like SSRIs and once-a-week talk therapy just doesn’t cut it for everyone anymore. That’s one of the reasons I started my own concierge psychiatry practice—to create space for a more nuanced, whole-person approach. Because real healing isn’t just about symptom relief or chasing quick fixes. It’s about addressing the why, not just the what.
Enter the chat: psychedelics and microdosing—not as miracle cures, but as potential tools in the mental wellness toolbox. So let’s dive in: What exactly is microdosing? Why are people doing it? And is it really as magical as all those wellness influencers make it out to be?
Let’s get into it—mindfully, responsibly, and with zero fluff.
Microdosing 101: The Basics
So, what is microdosing?
Microdosing refers to taking a very small, sub-perceptual amount of a psychedelic substance—most commonly psilocybin, the active compound in “magic mushrooms.” The dose is so small that you’re not meant to “trip” or hallucinate, but rather experience subtle shifts in your cognition—think increased clarity, focus, creativity, and emotional regulation.
In this dose range, we’re talking about 5–10% of a typical hallucinogenic dose. The kind of amount that won’t have you thinking your potted house plant is giving you life advice, but might help you finally get through your inbox without spiraling.
Why Are People Doing It?
Because they’re curious, because they’re tired of being numb, and because some swear it helps them feel more alive, more connected, more… them.
Some of the most frequently shared reasons for microdosing include:
- Mood improvement
- Enhanced creativity and productivity
- Reduced anxiety or depressive symptoms
- Support during life transitions (hello, existential 30s, 40s, or 50s)
- Alternative to daily pharmacotherapy with unwanted side effects
It’s not about escaping reality—it’s about tuning in. Many users describe feeling “lighter,” “more present,” or “less reactive” to life’s daily chaos (which we could all use, am I right?).
Is It Legal?
Ah, the million-dollar question.
Short answer: In most of the United States, psilocybin is still illegal federally. However, a few progressive cities and states have decriminalized it (like Oregon and parts of Colorado and California). This means that enforcement may be lower in these areas, but technically, it’s still not a legal “free-for-all.” Always check your local laws before considering exploring.
Internationally, some countries like the Netherlands have more lenient policies. While psilocybin mushrooms are technically illegal there, psilocybin truffles—AKA sclerotia, a naturally occurring underground part of the fungus—are legal and sold openly in smart shops meant to be used recreationally.
What Is It Used For?
Microdosing is not officially FDA-approved for medical use, but ongoing scientific research suggests potential benefits in areas like:
Depression (especially in chronic, treatment-resistant forms)
PTSD
Anxiety
Addiction
Cognitive decline and neuroplasticity
Enhancing well-being in healthy individuals; longevity
It’s often described as a “mental reset” or a “mood booster without the crash.” So while this sounds promising, remember: anecdote is not the same as data. And while studies are emerging, we still need more robust, long-term research to validate these claims fully. Especially with regard to safety, and what populations would benefit from them.
What Does It Do for the Mind or Body?
Microdosing seems to increase brain connectivity and reduce activity in the default mode network—essentially, the part of the brain linked to rumination and self-referential thought (you know, the mental loop of “why did I say that dense thing in 2016”?).
Some report feeling more “open,” emotionally attuned, or less caught up in overthinking.
Physically, some people feel a gentle energizing sensation, though this again varies significantly per person.
If You Were to Try It (Hypothetically), What Should You Look For?
Let’s say you’re traveling somewhere where it is legal and considering trying it out—what should you look for to ensure efficacy and safety?
Here’s the checklist:
- Lab-tested product: No one needs surprise contaminants.
- Known dosage: Start low. Micro = micro.
- Set & Setting: Your mindset and environment matter—even with a microdose.
- Quality sourcing: Work with reputable brands or providers. Avoid back-alley “bro-science.”
- Track your experience: Many use journals or apps to track mood and focus shifts.
- And please, never mix with other medications or alcohol unless guided by a trained medical professional who knows your personal health history.
Final Thoughts
Microdosing isn’t a magic fix, nor is it a substitute for deep, consistent mental health work—but it’s part of a new wave of curiosity around healing, presence, and performance. It’s okay to ask questions. It’s okay to explore alternatives (safely and legally). And it’s okay to want to feel more like you again.
As with any trend—whether it’s biohacking, breathwork, or brain-boosting mushrooms—stay informed, stay safe, and stay curious. You deserve to feel well—and to do so intentionally.
More about Mona
Psychiatrist | Speaker | Architect of Innovative Mental Health Dr. Mona Amini MD, MBA, is an exceptional figure in the realm of psychiatry, a testament to ingenuity and excellence. As a board-certified psychiatrist, her clinical acumen is augmented by an MBA, underscoring a multidimensional approach that blends patient-centric care with strategic healthcare management. Her innovative spirit propels her beyond conventional medical practice, as she addresses the intricate challenges of mental health with unmatched dedication and insight. Dr. Amini's voice boldly attempts to shatter the silence surrounding once-taboo topics in mental health, championing the urgent need for open dialogue and progressive change. Her relentless pursuit of breaking barriers and fostering understanding cements her status as a vanguard of mental wellness, inspiring countless others to join in transforming the landscape of mental healthcare. In the pursuit of superior patient outcomes, Dr. Amini has been steadfast. Her meticulous attention to detail ensures that care delivery is not just thorough, but also tailored to individual needs. Recognizing the evolving landscape of healthcare, she has pioneered a concierge mental wellness practice unlike any other. This cutting-edge approach offers a subscription-based model that integrates medication management, personalized practical psychotherapy, IV wellness treatments, and comprehensive lab testing, all-inclusive and all within the comfort and privacy of the patient's home. Dr. Amini exemplifies leadership that extends the frontiers of traditional healthcare. Her advocacy for mental wellness is not confined to the clinical setting; she actively disseminates vital knowledge and spearheads educational efforts to highlight critical mental health issues within her community and the public. She has served in multiple executive roles and as past President of the Arizona Psychiatric Society (regional chapter of the American Psychiatric Association) in addition to serving as a member of local medical and global media organizations. Dr. Amini is deeply invested in the professional growth of her peers, particularly in mentoring female healthcare professionals, thus nurturing a culture of diversity, support, and empowerment within the sector. She founded the Arizona Psychiatric Society's Women's Group in 2016 with this such aim. With a voice both articulate and compelling, Dr. Amini is not just leading developments in mental wellness; she is setting the pace. Her commitment to sharing her expansive knowledge and fostering a community of learning positions her as a luminary in the field, shaping the contours of mental wellness leadership for the present and the future.